The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

Dr Paula Cevaal

Dr Paula Cevaal

Dr Paula Cevaal

+61 3 834 43216 | paula.cevaal@unimelb.edu.au

Position:
Research Fellow
Theme(s):
Viral Infectious Diseases, HIV
Unit(s):
The University of Melbourne, Department of Infectious Diseases
Lab Group(s):
Lewin Group

Dr Paula Cevaal is a post-doctoral scientist in the lab of Professor Sharon Lewin. She received her MSc training in The Netherlands, specialising in infectious diseases and immunology. She then spent a year doing youth advocacy work at AIDS2018, after which she completed a joint PhD in virology and nanomedicine. Her work focuses on developing non-viral vectors to efficiently deliver therapeutics to primary CD4+ T cells. Specifically, she led a new line of research pioneering lipid nanoparticles for the delivery of mRNA-based latency-reversing agents to the latent HIV reservoir. The overarching goal of her work is to take gene editing-related strategies to the clinic.

  • Key Achievements
    • Paula Cevaal is a J and M Wright Fellow. Her work pioneering nanoparticle delivery to T cells has received national and international funding that led to the acquisition of the first NanoAssemblr microfluidic mixing system for the formulation of mRNA-lipid nanoparticles within the University of Melbourne. She is a named inventor on two patent applications related to this work and was awarded the prestigious Young Investigator Award at the International AIDS Society meeting in 2023.

    Publications
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    Research Groups
    • Lewin Group

      The focus of the Lewin group is to understand why HIV infection persists on antiretroviral therapy and to develop new strategies to eliminate latency. The lab also researches factors that drive liver disease in HIV-hepatitis B virus co-infection. The lab is also actively involved in COVID in relation to pathogenesis, the use of primary tissue models, and developing therapeutics using gene editing strategies.


      Lab Team

      Lewin Group

      • Director - The Peter Doherty Institute for Infection and Immunity
      • Deputy Head Lewin Lab | Senior Research Fellow
      • Senior Research Fellow
      • Dr Wei Zhao
        Research Fellow
      • Dr Chris Chiu
        Research Fellow
      • Dr Youry Kim
        Research Fellow
      • Dr Stan Kan
        Research Fellow
      • Postdoctoral Research Fellow
      • Clinical Research Liason Officer
      • Dr Judy Chang
        Research Systems Administrator
      • Senior Research Officer
      • Research Coordinator
      • Laboratory Manager
      • Infectious Diseases Physician
      • Research Fellow
      • Research Fellow
      • Carolin Tumpach
        Research Support Officer
      • Rosalyn Cao
        Research Support Officer
      • Danielle Fong
        Research Support Officer
      • Abigail Tan
        Research Support Officer
      • Jared Stern
        PhD Candidate
      • Rachel Pascoe
        PhD Candidate
      • Haoming Liu
        PhD Candidate
      • Kiho Tanaka
        PhD Candidate
      • Rory Shepherd
        PhD Candidate
      • Lauren Wallace
        Honours Student
      • Bridget Fisher
        Honours Student
      • Associate Professor Edwina Wright
        Clinical Affiliate
      • Dr James McMahon
        Clinical Affiliate
      • Head, Clinical Virology and HIV Services, Deputy Director Department of Infectious Diseases Austin Health
      • Associate Clinical Director of HIV Cure Studies