Adam Uldrich | Doherty Website

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Adam Uldrich

Adam Uldrich

+61 3 9035 5744 | auldrich@unimelb.edu.au

Position:: Senior Research Fellow
Theme(s):: Immunology
Discipline(s):: Discovery Research
Unit(s):: The University of Melbourne, Department of Microbiology and Immunology (DMI)

Dr Adam Uldrich is a senior research fellow at the Department of Microbiology and Immunology (DMI), University of Melbourne. After performing post-doctoral studies at the Peter MacCallum Cancer Centre, examining the role of unconventional T cells in tumor immune surveillance, he then joinedDMI in 2010. Here he has established a research programme with a focus on gamma-delta T cell biology. His research interests include understanding the molecular mechanisms that underpin gamma-delta T cell-mediated immunity.

Key Achievements
Publications

Key Achievements
- Recently, the Uldrich Lab identified a key role for a family of proteins known as butyrophilins in gamma-delta T cell immunity. This has resulted in some impactful publications, including:
  
  1. Vγ9Vδ2 T cells recognize butyrophilin 2A1 and 3A1 heteromers
  
  (Fulford TS, Soliman C, Castle RG, Rigau M, Ruan Z, Dolezal O, Seneviratna R, Brown HG, Hanssen E, Hammet A, Li S, Redmond SJ, Chung A, Gorman MA, Parker MW, Patel O, Peat TS, Newman J, Behren A, Gherardin NA, Godfrey DI, Uldrich AP. Nature Immunology 2024 Aug;25(8):1355-1366. DOI: https://doi.org/10.1038/s41590-024-01892-z)
  
  2. Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells
  
  (Rigau M, Ostrouska S, Fulford TS, Johnson DN, Woods K, Ruan Z, McWilliam HEG, Hudson C, Tutuka C, Wheatley AK, Kent SJ, Villadangos JA, Pal B, Kurts C, Simmonds J, Pelzing M, Nash AD, Hammet A, Verhagen AM, Vairo G, Maraskovsky E, Panousis C, Gherardin NA, Cebon J, Godfrey DI, Behren A, Uldrich AP. Science. 2020 Feb 7;367(6478):eaay5516. DOI: https://doi.org/10.1126/science.aay5516)
Publications

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