The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

Our Work | COVID-19

Clinical and Public Health

Australasian COVID-19 Trial (ASCOT)

The Australasian COVID-19 Trial (ASCOT) is a randomised controlled trial that will generate clinical evidence about treatments for COVID-19. The ASCOT trial is being run as an Adaptive Platform Trial (APT), allowing for the study to have multiple interventions in a disease or condition by adding or removing treatment interventions to the trial as resulting data is generated and analysed. The trial will recruit patients hospitalised with COVID-19 who do not yet require intensive care support, with the aim of preventing deterioration to the point of requiring intensive care. The ASCOT trial collaborates closely with another COVID-19 platform trial – the Randomised, Embedded, Multi-factorial, Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP), that evaluates the efficacy and safety of particular drugs to treat patients admitted to intensive care with community-acquired pneumonia.

Project lead

Funders

  • Royal Brisbane Hospital Foundation
  • APPRISE
  • Pratt Foundation
  • BHP
  • Minderoo Foundation
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