Antimicrobial Resistance|People

Scott group

The Scott group focuses on the identification and characterisation microbial mediate protein glycosylation. This post translational modification allows pathogens to radically alter the function of proteins both within them, and their hosts. Within a range of pathogens such as malaria and Burkholderia, microbial protein glycosylation is used for both defensive and offensive processes, enabling pathogens to fortify themselves against the host immune response or to disarm the host’s ability to resist infection. Using mass spectrometry-based approaches, the Scott group seeks to develop methodologies to identify and track microbial glycosylation events to understand how microbes remodel their proteome and that of the hosts.