Project: Population genetic methods for modelling bacterial pathogen evolution
Davies Group
Bacterial disease is a major global economic burden fuelled by the ability of bacteria to become resistant to drugs and vaccines. Bacteria have such capacity because they can rapidly alter their genetic material. This project aims to create sophisticated statistical and computational techniques to analyse large genomic databases to study how harmful bacteria evolve. This project will provide in-depth understanding of this process, which will aid in devising affordable, long-term solutions to prevent bacterial diseases.
Project Site: The Peter Doherty Institute for Infection and Immunity & Peter MacCallum Cancer Centre
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Davies Group
4 vacancies
The Davies group aims to apply genome sequencing methodologies and bioinformatics approaches to understand the evolution and transmission of bacterial pathogens. This knowledge can help facilitate a global understanding of pathogen evolution, in addition to informing public health interventions to reduce the disease burden associated with bacterial pathogens. A particular focus of our group is understanding disease processes within regions where disease burden is the highest.
Davies Group Current Projects
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Population genetic methods for modelling bacterial pathogen evolution
PhD/MPhil, Master of Biomedical Science, Honours
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Unravelling the drivers of group A streptococcal pandemics
PhD/MPhil, Master of Biomedical Science, Honours
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Population genomics of endemic Streptococcus pyogenes
PhD/MPhil, Master of Biomedical Science, Honours
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Characterising the evolutionary and metabolic profile of streptococcal pathogens
PhD/MPhil, Master of Biomedical Science, Honours
Research degrees at the Doherty Institute are administered by the University of Melbourne.