Project: Mapping the impact of antibody and B cell memory on secondary antigen exposure
Wheatley Group
Boosting immunity established by prior infection or previous vaccines is complex, with differential contributions from naïve and memory B cells, and the impact of pre-existing antibody. This projects seeks to use transgenic mouse models to map the kinetics and localisation of immune lymphocytes during secondary antigen exsposures.
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Wheatley Group
3 vacancies
The Wheatley group is interested in factors that program broad and durable humoural immunity against infectious pathogens such as SARS-CoV2 and influenza. Our research involves immunological charactersiaton of B cells and antibodies, development of assays and tools to study antiviral immunity, novel vaccine design and the development of monoclonal antibodies to treat or prevent infections.