Project: Characterising the evolutionary and metabolic profile of streptococcal pathogens
Davies Group
Horizontal gene flow between closely related bacteria can shape the evolutionary trajectory of key streptococcal pathogens. Preliminary data from our laboratory have indicated that changes in metabolic pattern of streptococci may play an important role in the maintenance of these pathogens in disease rich settings. This project will define the metabolomic profile of group A, C and G streptococci through high-throughput phenomics and relate this to the genomic makeup of the organism. This study will address crucial knowledge gaps in these major bacterial pathogens.
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Davies Group
4 vacancies
The Davies group aims to apply genome sequencing methodologies and bioinformatics approaches to understand the evolution and transmission of bacterial pathogens. This knowledge can help facilitate a global understanding of pathogen evolution, in addition to informing public health interventions to reduce the disease burden associated with bacterial pathogens. A particular focus of our group is understanding disease processes within regions where disease burden is the highest.
Davies Group Current Projects
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Population genetic methods for modelling bacterial pathogen evolution
PhD/MPhil, Master of Biomedical Science, Honours
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Unravelling the drivers of group A streptococcal pandemics
PhD/MPhil, Master of Biomedical Science, Honours
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Population genomics of endemic Streptococcus pyogenes
PhD/MPhil, Master of Biomedical Science, Honours
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Characterising the evolutionary and metabolic profile of streptococcal pathogens
PhD/MPhil, Master of Biomedical Science, Honours
Research degrees at the Doherty Institute are administered by the University of Melbourne.