Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan

Author(s):

Carolien E. van de Sandt, Thi H.O. Nguyen, Nicholas A. Gherardin, Jeremy Chase Crawford, Jerome Samir, Anastasia A. Minervina, Mikhail V. Pogorelyy, Simone Rizzetto, Christopher Szeto, Jasveen Kaur, Nicole Ranson, Sabrina Sonda, Alice Harper, Samuel J. Redmond, Hayley A. McQuilten, Tejas Menon, Sneha Sant, Xiaoxiao Jia, Kate Pedrina, Theo Karapanagiotidis, Natalie Cain, Suellen Nicholson, Zhenjun Chen, Ratana Lim, E. Bridie Clemens, Auda Eltahla, Nicole L. La Gruta, Jane Crowe, Martha Lappas, Jamie Rossjohn, Dale I. Godfrey, Paul G. Thomas, Stephanie Gras, Katie L. Flanagan, Fabio Luciani, Katherine Kedzierska

Details:

Nature Immunology, Volume 24, Issue 11, 2023-11-01

Article Link: Click here

Affiliations:

• The Peter Doherty Institute for Infection and Immunity
• Cardiff University School of Medicine
• University of Melbourne
• St. Jude Children's Research Hospital
• Faculty of Medicine, Nursing and Health Sciences
• UNSW Medicine
• RMIT University
• La Trobe University
• Launceston General Hospital
• Tasmanian School of Medicine
• Royal Melbourne Hospital
• Universiteit van Amsterdam
• Deepdene Surgery